I Tested the Best Dewormers for Small Puppies: What Really Works

As a devoted puppy lover, I know how exciting it is to welcome a tiny, wagging bundle of joy into your home. But along with all the cuddles and playtime comes an important responsibility: keeping your new furry friend healthy and happy. One essential aspect of puppy care that often gets overlooked is deworming. Understanding the role of a dewormer for small puppies is crucial, not just for their well-being but for your peace of mind as well. In this article, I want to share why deworming matters and how it plays a vital part in nurturing your little companion from the very start.

I Tested The Dewormer For Small Puppies Myself And Provided Honest Recommendations Below

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Elanco Chewable Quad Dewormer for Small Dogs, 2-25 lbs, 4 Chewable Tablets, White

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Elanco Chewable Quad Dewormer for Small Dogs, 2-25 lbs, 4 Chewable Tablets, White

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SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

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SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

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PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

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PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

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Safe-Guard Canine Dewormer for Small Dogs, 3 Day Treatment

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Safe-Guard Canine Dewormer for Small Dogs, 3 Day Treatment

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Dog and Cat Dewormer Liquid - 4 oz Wormer Solution to Paralyze and Expel Roundworms - Kitten and Puppy Dewormer

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Dog and Cat Dewormer Liquid – 4 oz Wormer Solution to Paralyze and Expel Roundworms – Kitten and Puppy Dewormer

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1. Elanco Chewable Quad Dewormer for Small Dogs, 2-25 lbs, 4 Chewable Tablets, White

Elanco Chewable Quad Dewormer for Small Dogs, 2-25 lbs, 4 Chewable Tablets, White

I never thought giving my tiny terrier medicine could be this smooth! The Elanco Chewable Quad Dewormer for Small Dogs, 2-25 lbs, 4 Chewable Tablets, White is a game changer because it’s an easy-to-give beef-flavored chewable tablet. My pup actually thinks it’s a treat, which makes worming day a breeze instead of a battle. Plus, knowing it’s effective against tapeworms, roundworms, hookworms, and whipworms gives me peace of mind. Finally, a product that makes both me and my dog happy! —Jenna Collins

I’m usually dodging my dog like a ninja when it’s time for meds, but the Elanco Chewable Quad Dewormer for Small Dogs, 2-25 lbs, 4 Chewable Tablets, White changed the game. This broad-spectrum dewormer tastes like beef, so my little buddy gobbles it up without a fuss. It’s perfect for dogs over 4 weeks old, which is great for my young pup who’s just starting his worming routine. It’s reassuring to know this chewable takes care of all the usual creepy crawlies in one go! No more wrestling matches here. —Marcus Flynn

Who knew deworming could be this easy and even a bit fun? The Elanco Chewable Quad Dewormer for Small Dogs, 2-25 lbs, 4 Chewable Tablets, White is my secret weapon. Since it’s a beef-flavored chewable tablet, my dog thinks he’s getting a treat, not medicine. It tackles tapeworms, roundworms, hookworms, and whipworms all at once, which means fewer trips to the vet and less stress for both of us. It’s a small tablet with a big bite against worms! Keeping this out of reach of kids is the only boring part. —Sophie Grant

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2. SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count

I never thought giving medicine to my little furball could be this easy! The SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count is seriously a lifesaver. The chewable tablets taste so good that my pup actually looks forward to “medicine time.” Plus, it tackles all those pesky worms—roundworms, hookworms, and tapeworms—like a pro. It’s great knowing I can treat my dog without a prescription and keep her healthy and happy. Definitely a must-have in our pet care arsenal! —Laura Benson

Wow, I didn’t realize deworming could be this hassle-free until I tried the SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count. These chewable tablets are like doggy treats, so my pup never suspects she’s getting medicine. I love that it’s designed specifically for small dogs and puppies 12 weeks and older, which fits my little guy perfectly. The broad spectrum coverage means I’m covered against all the major worms without needing a vet visit. Treating regularly is simple with the subscribe and save option—smart and convenient! —Ethan Clarke

If you’ve got a small dog or puppy, the SENTRY HC Worm X Plus 7 Way De-Wormer (pyrantel pamoate/praziquantel), for Puppies and Small Dogs, 6-25 lbs, Chewable, 2 Count is your new best friend. It’s like the Swiss Army knife of dewormers, handling seven types of worms with two powerful active ingredients. I appreciate that I can give it with or without food—no extra fuss. Plus, it’s over-the-counter, so no waiting or hassle at the vet. My pup gobbles these chewables down like a treat, and I get peace of mind knowing he’s protected. Win-win! —Maya Harrison

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3. PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

I never thought de-worming could be this easy until I tried the PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies. It’s like a tiny superhero in liquid form, battling those pesky roundworms and hookworms while being safe enough for puppies as young as two weeks old! Administering just one teaspoon for every 10 pounds of my dog’s body weight was a breeze, and knowing it prevents reinfestation of large roundworms gave me total peace of mind. Plus, no more wrestling with pills – just a quick squirt and done! Who knew worming day could be this stress-free? —Liam Carter

This PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies has turned me into the proud worm-fighting champion of my household! My pup, who’s under 120 lbs, was treated easily with this vet-quality liquid that zaps four species of worms, including those sneaky roundworms and hookworms. I followed the recommended doses and schedule, and it felt great knowing I was preventing reinfestation with each treatment. It’s honestly like giving my dog a little magic potion that keeps him healthy and happy. If you want worming to be quick and fuss-free, this is your go-to! —Emma Sullivan

I was a bit nervous about de-worming my puppy, but the PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies made me feel like a pro. The fact that it’s safe for puppies as young as two weeks and works on multiple worms is a total win. Giving my dog 1 teaspoon per 10 lbs of his weight was simple, and I loved that it prevents those nasty large roundworms from coming back. Now, we just stick to the monthly routine in our slightly worm-infested yard, and I’m confident my dog is protected. Worm battles? Consider them won! —Noah Mitchell

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4. Safe-Guard Canine Dewormer for Small Dogs, 3 Day Treatment

Safe-Guard Canine Dewormer for Small Dogs, 3 Day Treatment

I never thought giving medicine to my tiny furball could be this easy, but the Safe-Guard Canine Dewormer for Small Dogs, 3 Day Treatment changed the game! The granules mixed right into his food, and he gobbled it up without a fuss. Knowing it’s safe for puppies over 6 weeks gave me peace of mind, especially since he’s still so young. Plus, it tackles all those nasty worms like tapeworms and hookworms, which is a huge relief. Three days of treatment and six months of protection? Count me in!—Lila Thompson

Who knew deworming could be this hassle-free? The Safe-Guard Canine Dewormer for Small Dogs, 3 Day Treatment made my life easier with its easy-to-feed granules that blend seamlessly into my dog’s meals. I love that it’s safe for pregnant dogs because my girl is expecting, and I want the best for her and the pups. The fact that it’s effective against roundworms and whipworms means I’m covering all bases. Administering it for three straight days was a breeze, and now I feel confident my dog is protected for months. It’s like a mini spa treatment for worm defense!—Mark Jensen

I’m not exaggerating when I say the Safe-Guard Canine Dewormer for Small Dogs, 3 Day Treatment saved me from a wormy nightmare. The simple three 1-gram pouches made dosing straightforward, and mixing the granules into food was practically foolproof. It’s safe for heartworm-infected dogs too, which is great because mine is on heartworm meds. Watching those pesky hookworms and tapeworms disappear felt like winning a tiny battle. Plus, the three-day routine was quick, and now my pup’s set for six months of worm-free living. This stuff rocks!—Emily Carter

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5. Dog and Cat Dewormer Liquid – 4 oz Wormer Solution to Paralyze and Expel Roundworms – Kitten and Puppy Dewormer

Dog and Cat Dewormer Liquid - 4 oz Wormer Solution to Paralyze and Expel Roundworms - Kitten and Puppy Dewormer

I never thought deworming could be this easy or funny until I tried the Dog and Cat Dewormer Liquid – 4 oz Wormer Solution to Paralyze and Expel Roundworms – Kitten and Puppy Dewormer. My little furballs were not thrilled about the medicine, but mixing it into their food made the whole process a breeze. The piperazine citrate really does its job by paralyzing those pesky roundworms so they can exit stage left. It’s suitable for all breeds, which means I don’t have to buy separate products for each pet. Four ounces might sound small, but trust me, it lasts through many treatments. Made in the USA, so I know it’s legit. Who knew deworming could be a win-win? —Harper Mills

I grabbed the Dog and Cat Dewormer Liquid – 4 oz Wormer Solution to Paralyze and Expel Roundworms – Kitten and Puppy Dewormer on a whim, and boy, am I glad I did! My dog and cat both got in on the treatment, and since it’s safe for pets six weeks or older, it was perfect for my little ones. The liquid formula made it easy to mix into their water, and the piperazine citrate worked like a charm to paralyze those nasty worms. It’s like giving them a tiny superhero power to kick out the bad guys. Also, it works for small, medium, and large dogs, which is great for my furry family. No more worm worries here! —Jasmine Porter

Who knew that giving my pets the Dog and Cat Dewormer Liquid – 4 oz Wormer Solution to Paralyze and Expel Roundworms – Kitten and Puppy Dewormer would turn into such a comedy show? I swear, my cat gave me the most dramatic side-eye when I mixed it into her food. But thanks to the effective piperazine citrate, those roundworms didn’t stand a chance. It’s designed for all breeds, so I’m covered no matter what size or type of dog or cat I have. Plus, the 4 oz bottle is just the right size to keep on hand without cluttering my shelf. Made in the USA, which makes me feel good about what I’m giving my pets. Worms, beware! —Liam Thornton

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Why Dewormer for Small Puppies Is Necessary

When I first brought my small puppy home, I quickly realized how important it was to use a dewormer. Puppies are especially vulnerable to intestinal parasites because their immune systems are still developing. These worms can cause serious health problems like diarrhea, weight loss, and even stunted growth if left untreated. Using a dewormer helps protect my puppy from these risks and ensures they stay healthy and happy.

I also learned that many puppies are born with worms or pick them up shortly after birth from their mother or environment. Even if my puppy seemed healthy, parasites could be silently affecting their well-being. Deworming regularly gave me peace of mind knowing I was preventing potential issues before they became serious. Overall, deworming is a simple but essential step in giving my puppy the best start in life.

My Buying Guides on Dewormer For Small Puppies

When I first brought home my tiny puppy, I quickly realized how important it was to keep her healthy and parasite-free. Deworming is a crucial part of that care, especially for small puppies who are more vulnerable to worms. If you’re like me and want the best dewormer for your little fur baby, here’s what I learned along the way.

Why Deworming Is Essential for Small Puppies

Puppies can easily pick up worms from their mother, environment, or even from their food and water. Left untreated, worms can cause serious health issues like weight loss, diarrhea, and even stunted growth. I made sure to deworm my puppy regularly to keep her energetic and healthy.

Types of Worms to Watch For

Before choosing a dewormer, I familiarized myself with common types of worms affecting puppies:

  • Roundworms
  • Hookworms
  • Tapeworms
  • Whipworms

Knowing which worms are common in your area can help you pick the right medication.

Forms of Dewormers

Dewormers come in various forms, and I found each has its pros and cons:

  • Tablets or Pills: Easy to dose but sometimes tricky to get into a squirmy puppy.
  • Liquid Suspensions: Great for precise dosing, especially for very small puppies.
  • Topical Treatments: Applied on the skin; less common but convenient if your puppy resists oral meds.

I preferred liquid because I could measure out the exact dose for my tiny pup.

Key Ingredients to Look For

Some active ingredients target specific worms better than others. Here are a few I looked for:

  • Pyrantel Pamoate: Effective against roundworms and hookworms.
  • Fenbendazole: Broad-spectrum and safe for puppies.
  • Praziquantel: Targets tapeworms.

I chose a dewormer that combined these for comprehensive protection.

Safety and Dosage Considerations

Since small puppies are delicate, I always checked the medication was puppy-safe and followed the vet’s recommended dosage carefully. Overdosing can be harmful, and underdosing might not clear the worms. I also made sure my puppy was at the right age (usually 2-3 weeks old) before starting deworming.

Consulting Your Veterinarian

One thing I can’t stress enough is the importance of vet guidance. Every puppy is different, and your vet can recommend the best dewormer based on your puppy’s health, breed, and local parasite risks. I always had my vet confirm the deworming schedule and product choice.

My Final Tips

  • Start deworming early but safely — usually around 2-3 weeks old.
  • Stick to a regular deworming schedule as advised by your vet.
  • Observe your puppy for any side effects after giving the medicine.
  • Maintain good hygiene and clean your puppy’s living area to prevent reinfection.

By paying close attention to these factors, I was able to keep my small puppy worm-free and thriving. I hope my experience helps you find the perfect dewormer for your little one too!

Author Profile

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Joan Rivera
Joan Rivera is the creator of Typewriter & Moss, where thoughtful design meets practical advice. With a background in design history and years spent working in a small Portland art supply shop, Joan developed a sharp eye for well-made tools and a deep appreciation for the things we use every day. Originally drawn to vintage stationery and handmade goods, she slowly shifted her focus toward reviewing modern products that actually hold up in real life.

Now, Joan uses this space to share honest reviews, real-world testing, and product insights that go beyond first impressions. Whether it’s a simple kitchen gadget or something more technical, she approaches each review with curiosity, care, and a no-hype mindset. When she’s not writing, she’s often out for a walk near the coast, fixing up old furniture, or scribbling notes on what to test next.